Therapeutic Performance Mapping System (TPMS) technology enables the computational simulation of human pathophysiology, enhancing our understanding of the mechanisms underlying drugs' clinical responses. It has broad applications throughout the drug discovery and development process, providing crucial support for decision-making at each stage.
TPMS technology is particularly advantageous in early drug discovery, enabling the evaluation of candidate compounds for efficacy, safety, mechanism of action, as well as to identify new therapeutic targets and new indications of existing drugs. During later clinical stages, TPMS technology offers valuable insights for optimizing clinical trials and patient stratification through In Silico Clinical Trials, in addition to enhancing our understanding of the mechanism behind trial outcomes. Moreover, TPMS technology serves as a valuable tool for generating evidence surrounding products, further enhancing its utility in the field.